Introduction (What is Germicide?)
According to Wise
Geek “ A germicide is any type of product that is designed to kill germs
and bacteria on different types of surfaces”
Chemical germicides including
disinfectants and antiseptics are used in a variety of applications from
sterilizing medical instruments at hospitals to cleaning a household kitchen
counter. They provide a convenient method of inactivating a variety of
potentially harmful microorganisms.
Chemical germicides are known by
several names, including antimicrobials, disinfectants, sporicides, sanitizers
and sterilants, just to name a few. They are designed to destroy a variety of
pathogenic microorganisms such as viruses, bacteria, bacteria spores, molds and
fungi. They are divided into sterilants, disinfectants and antiseptics.
Sterilants kill microorganisms on
medical equipment and devices as well as surfaces. This includes bacterial
spores, which can survive other germicides. The EPA regulates disinfectants.
Disinfectants—which
can be classified as high-, medium-, or low-level depending on the strength
required—kill nearly all microbial life on objects or surfaces except for
bacterial spores.
Antiseptics
are used to inactivate or destroy organisms
on skin or living tissue.
Applications
Deciding which category of germicide
you want to use depends on the function of the device or surface that is being
considered. Steam autoclaving or ethylene oxide sterilization might damage
certain instruments, so use chemical germicides in those processes. Critical
devices—such as endoscopes, forceps and hemodialyzers—that enter sterile areas
of the body or protrude into the blood barrier must be sterilized.
Semi-critical devices—such as fiber-optic endoscopes, vaginal specula, and
dental and ophthalmic devices—that only contact mucous membranes and don't
penetrate body tissues can be sterilized or cleaned with a high-level
disinfectant, depending on the application. Non-critical devices that only
contact intact skin—such as stethoscopes, blood-pressure cuffs, electrodes and
measuring devices—may be cleaned with a low-level disinfectant. Equipment
surfaces including handles, knobs or carts, as well as housekeeping
surfaces—such as sinks, counters or floors—may also be cleaned with a low-level
disinfectant.
Germicidal Effectiveness
Many factors influence the
effectiveness of germicides, including the:
- shape of the object being cleaned, including its surface texture and whether it is flat or has cracks
- amount of microbiologicals on the surface
- resistance of the microbiologicals to the germicide
- amount of additional soil buildup on the object, including blood, mucous or tissue
- chemical composition of the germicide
- time of exposure to the germicide
- temperature of the germicide
Generally, bacterial spores—including
Bacillus subtilis—have the most resistance to germicides, followed by
mycobacteria such as Mycobacterium tuberculosis, non-lipid viruses such as
poliovirus, fungi such as Cryptococcus, vegetative bacteria such as Salmonella
choleraesuis, and lipid viruses such as human immunodeficiency virus with the
least resistance.
Because of the many factors that
affect germicides, each object that is to be cleaned must be analyzed for the
best method and germicide to use. It is of great importance to read and understand
the manufacturer's instructions to know which application the product is
designed for as well as the instructions for its proper use.
Ingredients (Mix the under listed materials
for maximum production)
Ingredient
|
Sterilization
Concentration
|
Disinfection
|
|
Concentration
|
Activity
Level
|
||
Glutaraldehyde
|
variable
|
variable
|
H, M
|
Alcohols
|
none
|
70%
|
M
|
Chlorine Dioxide
|
variable
|
variable
|
H
|
Chlorine mixtures
|
none
|
500 to 5000mg
free chlorine |
M
|
Hydrogen Peroxide
|
6% to 30%
|
3% to 6%
|
H, M
|
Iodophor mixtures
|
none
|
40 to 50mg
free iodine |
M
|
Peracetic acid
|
variable
|
variable
|
M
|
Quaternary ammonium mixtures
|
none
|
0.1% to 0.2%
|
L
|
For one to go into production he must
provide or keep certain things ready for the production to go on. Such things as: (a) bowel, (b)
Contains preferably plastic contains, (c) Mixer, (d) labels and above all must
be registered with the relevant authorities in his country.
Regulators
The Environmental Protection
Agency's office of pesticides oversees disinfectants, including NBDAC in
Nigeria. Manufacturers are required to test products using pre-established test
procedures on product stability, toxicity to people and microbial activity. If
the product passes these requirements, it is registered by the agency and ready
for trade. The Food and Drug Administration oversees sterilants and germicides
that are required for a specific medical device. The manufacturers must submit
specific microbial activity data to the FDA before a pre-market notification or
510(k) being issued. Once the 510(k) is issued, the product is ready for trade.
The FDA also regulates antiseptics or drugs used on or in the human body. This
includes antimicrobial soaps, antiseptics, scrubs and wound protestants’, which
are simply categorized by an advisory panel that scrutinizes non-prescription
germicidal products. Manufacturers can voluntarily submit information on these
products.
|
||
|
The blood borne pathogens standard, 29
CFR 1910.1030, requires germicides. Housekeeping requirements mandate
decontamination and disinfection procedures for all equipment and working
surfaces when they contact blood or other potentially infectious materials.
In addition, general work practices require that hand washing facilities be
made available. If they are not feasible, an antiseptic hand cleanser and towels
or antiseptic towelettes must be available. For more information on the blood
borne pathogens standard, see Quick Tips #105: OSHA's Blood borne Pathogens Standard,
29 CFR 1910.1030.
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|
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The difference between Germicide and antiseptics
|
|
Disinfectants are designed for
objects and surfaces and are too strong for skin or tissue. Conversely,
antiseptics might are not strong enough to provide a thorough disinfection of
surfaces and objects. It is purposely made for body.
|
Sources
"Disinfection,
Sterilization, and Antiseptics in the Hospital", Martin S. Favre and
Walter W. Bond, Manual of Clinical Microbiology, American Society of
Microbiology, Washington DC, Chapter 24, pp. 183-200, 1991.
Occupational
Safety and Health Administration, 29 CFR 1910.1030, Blood borne Pathogens.
"Guidelines for Handwashing and Hospital Environmental Control", Revised by Julia S. Gardner, R.N., M.N. and Martin S. Favero, PhD, U.S. Department of Health & Human Services and Center for Disease Control and Prevention, 1987.
"Guidelines for Handwashing and Hospital Environmental Control", Revised by Julia S. Gardner, R.N., M.N. and Martin S. Favero, PhD, U.S. Department of Health & Human Services and Center for Disease Control and Prevention, 1987.
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